Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar 30:5:128.
doi: 10.1186/1752-1947-5-128.

Cecal obstruction due to primary intestinal tuberculosis: a case series

Affiliations

Cecal obstruction due to primary intestinal tuberculosis: a case series

Antonis Michalopoulos et al. J Med Case Rep. .

Abstract

Introduction: Primary intestinal tuberculosis is a rare variant of tuberculosis. The preferred treatment is usually pharmaceutical, but surgery may be required for complicated cases.

Case presentation: We report two cases of primary intestinal tuberculosis where the initial diagnosis was wrong, with colonic cancer suggested in the first case and a Crohn's disease complication in the second. Both of our patients were Caucasians of Greek nationality. In the first case (a 60-year-old man), a right hemicolectomy was performed. In the second case (a 26-year-old man), excision was impossible due to the local conditions and peritoneal implantations. Histopathology revealed an inflammatory mass of tuberculous origin in the first case. In the second, cell culture and polymerase chain reaction tests revealed Mycobacterium tuberculosis. Both patients were given anti-tuberculosis therapy and their post-operative follow-up was uneventful.

Conclusions: Gastrointestinal tuberculosis still appears sporadically and should be considered in the differential diagnosis along with other conditions of the bowel. The use of immunosuppressants and new pharmaceutical agents can change the prevalence of tuberculosis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Abdominal computed tomography revealing the site of the obstruction.
Figure 2
Figure 2
Double contrast barium enema revealing a stricture in the region of the ileo-cecal valve and ascending colon.
Figure 3
Figure 3
Tubercular mass of the cecum.
Figure 4
Figure 4
Contrast-enhanced abdominal computed tomography showing the cecal mass.
Figure 5
Figure 5
Intra-operative picture showing tubercular adhesions of the omentum and mesenterium, and small intestine enlargement.

References

    1. Sibartie V, Kirwan WO, O'Mahony S, Stack W, Shanahan F. Tuberculosis mimicking Crohn's disease: lessons relearned in a new era. Eur J Gastroenterol Hepatol. 2007;19:347–349. doi: 10.1097/MEG.0b013e328012122b. - DOI - PubMed
    1. Balamurugan R, Venkataraman S, John KR, Ramakrishna BS. PCR amplification of the IS6110 insertion element of Mycobacterium tuberculosis in fecal samples from patients with intestinal tuberculosis. J Clin Microbiol. 2006;44:1884–1886. doi: 10.1128/JCM.44.5.1884-1886.2006. - DOI - PMC - PubMed
    1. Chatzicostas C, Koutroubakis IE, Tzardi M, Roussomoustakaki M, Prassopoulos P, Kouroumalis EA. Colonic tuberculosis mimicking Crohn's disease: case report. BMC Gastroenterol. 2002;2:10. doi: 10.1186/1471-230X-2-10. - DOI - PMC - PubMed
    1. Epstein D, Watermeyer G, Kirsch R. The diagnosis and management of Crohn's disease in populations with high-risk rates for tuberculosis. Aliment Pharmacol Ther. 2007;25:1373–1388. doi: 10.1111/j.1365-2036.2007.03332.x. - DOI - PubMed
    1. Singh V, Kumar P, Kamal J, Prakash V, Vaiphei K, Singh K. Clinicocolonoscopic profile of colonic tuberculosis. Am J Gastroenterol. 1996;91:565–568. - PubMed

LinkOut - more resources