Specific adsorption of H-2-restricted cytotoxi T cells to macrophage monolayers
- PMID: 214513
- PMCID: PMC2185098
- DOI: 10.1084/jem.148.6.1711
Specific adsorption of H-2-restricted cytotoxi T cells to macrophage monolayers
Abstract
These experiments tested whether Tc cells specific for foreign antigen (X) plus self H-2 adsorbed to macrophage monolayers displaying (a) X with allogeneic H-2; (B) self H-2 alone; (c) X plus self H-2. Specific adsorption occurred only in case (c), a result compatible with altered self and requiring further operational assumptions in dual recognition models.
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