An update on hormone replacement therapy: health and medicine for women: a multidisciplinary, evidence-based review of mid-life health concerns
- PMID: 21451783
- PMCID: PMC3064244
An update on hormone replacement therapy: health and medicine for women: a multidisciplinary, evidence-based review of mid-life health concerns
Abstract
The Department of Obstetrics, Gynecology, and Reproductive Sciences at the Yale School of Medicine hosted a daylong continuing medical education (CME) symposium titled "Health and Medicine for Women: A Multidisciplinary, Evidence-Based Review of Mid-Life Health Concerns" in September 2010. A number of speakers discussed current research on hormone replacement therapy (HRT) and re-evaluated the results of the Women's Health Initiative (WHI), a landmark, randomized, placebo-controlled trial that still sparks debate almost a decade after its conclusion. This article summarizes this discussion and highlights directions for future study.
References
-
- Manson JE. et al. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med. 2003;349(6):523–534. - PubMed
-
- Chlebowski RT. et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women’s Health Initiative Randomized Trial. JAMA. 2003;289(24):3243–3253. - PubMed
-
- Mikkola TS, Clarkson TB. Estrogen replacement therapy, atherosclerosis, and vascular function. Cardiovasc Res. 2002;53(3):605–619. - PubMed
-
- Hsia J. et al. Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative. Arch Intern Med. 2006;166(3):357–365. - PubMed
-
- Hulley S. et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA. 1998;280(7):605–613. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical