Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar;84(1):39-42.

An update on hormone replacement therapy: health and medicine for women: a multidisciplinary, evidence-based review of mid-life health concerns

Affiliations

An update on hormone replacement therapy: health and medicine for women: a multidisciplinary, evidence-based review of mid-life health concerns

Lydia L Shook. Yale J Biol Med. 2011 Mar.

Abstract

The Department of Obstetrics, Gynecology, and Reproductive Sciences at the Yale School of Medicine hosted a daylong continuing medical education (CME) symposium titled "Health and Medicine for Women: A Multidisciplinary, Evidence-Based Review of Mid-Life Health Concerns" in September 2010. A number of speakers discussed current research on hormone replacement therapy (HRT) and re-evaluated the results of the Women's Health Initiative (WHI), a landmark, randomized, placebo-controlled trial that still sparks debate almost a decade after its conclusion. This article summarizes this discussion and highlights directions for future study.

PubMed Disclaimer

References

    1. Manson JE. et al. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med. 2003;349(6):523–534. - PubMed
    1. Chlebowski RT. et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women’s Health Initiative Randomized Trial. JAMA. 2003;289(24):3243–3253. - PubMed
    1. Mikkola TS, Clarkson TB. Estrogen replacement therapy, atherosclerosis, and vascular function. Cardiovasc Res. 2002;53(3):605–619. - PubMed
    1. Hsia J. et al. Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative. Arch Intern Med. 2006;166(3):357–365. - PubMed
    1. Hulley S. et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA. 1998;280(7):605–613. - PubMed

LinkOut - more resources