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Practice Guideline
. 2011 Jul;54(1):328-43.
doi: 10.1002/hep.24330.

Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases

Bruce R Bacon  1 , Paul C Adams, Kris V Kowdley, Lawrie W Powell, Anthony S Tavill; American Association for the Study of Liver Diseases
Collaborators, Affiliations
Free PMC article
Practice Guideline

Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases

Bruce R Bacon et al. Hepatology. 2011 Jul.
Free PMC article
No abstract available

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Figures

Fig. 1
Fig. 1
Schematic representation of the protein product of HFE. Most of the protein is extracellular. There is a short cytoplasmic tail and three extracellular alpha loops. The three principal mutations are identified.
Fig. 2
Fig. 2
Summary of interactions between duodenal enterocytes, hepatocytes, and macrophages in iron homeostasis regulated by hepcidin. FPN, ferroportin. (Adapted from Camaschella C. BMP6 orchestrates iron metabolism. Nat Genet 2009;41:386–388. Used with permission from Nature Genetics. Copyright © 2009, Nature Publishing Group).
Fig. 3
Fig. 3
An algorithm can provide some further direction regarding testing and treatment for HH. The algorithm is modified from the version used in the previous AASLD guidelines.
See this image and copyright information in PMC

References

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    1. American Gastroenterological Association policy statement on the use of medical practice guidelines by managed care organizations and insurance carriers. Gastroenterology. 1995;108:925–926. - PubMed
    1. American College of Cardiology/American Heart Association. Methodology Manual for ACC-AHA Guideline Writing Committees: Methodologies and Policies from the ACC/AHA Task Force on Practice Guidelines, April. 2006.
    1. Shiffman RN, Shekelle P, Overhage JM, Slutsky J, Grimshaw J, Deshpande AM. Standardized reporting of clinical practice guidelines: a proposal from the Conference on Guideline Standardization. Ann Intern Med. 2003;139:493–498. - PubMed
    1. Phatak PD, Bonkovsky HL, Kowdley KV. Hereditary hemochromatosis: time for targeted screening. Ann Intern Med. 2008;149:270–272. - PubMed

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