How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General
- PMID: 21452462
- Bookshelf ID: NBK53017
How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General
Excerpt
In 1964, the Surgeon General released a landmark report on the dangers of smoking. During the intervening 45 years, 29 Surgeon General’s reports have documented the overwhelming and conclusive biologic, epidemiologic, behavioral, and pharmacologic evidence that tobacco use is deadly. Our newest report, How Tobacco Smoke Causes Disease, is a comprehensive, scientific discussion of how mainstream and secondhand smoke exposures damage the human body. Decades of research have enabled scientists to identify the specific mechanisms of smoking-related diseases and to characterize them in great detail. Those biologic processes of cigarette smoke and disease are the focus of this report.
Sections
- Message from Kathleen Sebelius
- Foreword
- Preface
- Acknowledgments
- 1. Introduction, Evaluation of Evidence on Mechanisms of Disease Production, and Summary
- 2. The Changing Cigarette
- 3. Chemistry and Toxicology of Cigarette Smoke and Biomarkers of Exposure and Harm
- 4. Nicotine Addiction: Past and Present
- 5. Cancer
- 6. Cardiovascular Diseases
- 7. Pulmonary Diseases
- 8. Reproductive and Developmental Effects
- 9. A Vision for the Future
- List of Abbreviations
- Definitions and Alternative Nomenclature of Genetic Symbols Used in This Report
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