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. 2011 Apr;20(4):585-90.
doi: 10.1158/1055-9965.EPI-10-1257.

Vitamin D: marker or mechanism of action?

Elizabeth T Jacobs  1 , María Elena Martínez, Peter W Jurutka
Affiliations

Vitamin D: marker or mechanism of action?

Elizabeth T Jacobs et al. Cancer Epidemiol Biomarkers Prev. 2011 Apr.

Abstract

The field of vitamin D and cancer research has been moving forward quickly. However, some challenges remain regarding the interpretation and integration of data collected from epidemiological investigations and laboratory experiments. These include consideration of vitamin D biology, a better understanding of characteristics that affect concentrations of the biomarker of vitamin D status, 25(OH)D, and elucidation of variation in response to vitamin D supplementation. To further the field of vitamin D and cancer prevention, future studies will need to bridge the gap between the epidemiology and molecular biology of vitamin D activity in carcinogenesis.

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Figures

Figure 1
Figure 1
Contributors to circulating concentrations of 25(OH)D.
Figure 2
Figure 2
Body size and physical activity as they relate to 25(OH)D concentrations.
See this image and copyright information in PMC

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