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. 2011 Apr;19(4):635-8.
doi: 10.1038/mt.2011.41.

Comparison of human induced pluripotent and embryonic stem cells: fraternal or identical twins?

Kazim H Narsinh  1 , Jordan Plews, Joseph C Wu
Affiliations

Comparison of human induced pluripotent and embryonic stem cells: fraternal or identical twins?

Kazim H Narsinh et al. Mol Ther. 2011 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Schematic of human embryonic stem cell (hESC) and human induced pluripotent stem cell (hiPSC) derivation protocols. (a) ESCs are derived from the inner cell mass (ICM) of the blastocyst, whereas (b) iPSCs can be derived from a variety of somatic cell types using a variety of reprogramming techniques. Commonly used assays to determine the equivalence of hESCs and hiPSCs at the molecular and functional levels are listed in the table on the right.
See this image and copyright information in PMC

References

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    1. Narsinh KH, Sun N, Sanchez-Freire V, Lee AS, Almeida P, Hu S, et al. J Clin Invest. e-pub ahead of print 7 February 2011; 2011. Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. - PMC - PubMed
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    1. Bock C, Kiskinis E, Verstappen G, Gu H, Boulting G, Smith ZD, et al. Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell. 2011;144:439–452. - PMC - PubMed
    1. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282:1145–1147. - PubMed

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