Review
doi: 10.1016/j.mrfmmm.2011.03.009.
Epub 2011 Mar 30.
MicroRNA history: discovery, recent applications, and next frontiers
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- PMID: 21458467
- DOI: 10.1016/j.mrfmmm.2011.03.009
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Review
MicroRNA history: discovery, recent applications, and next frontiers
Mutat Res.
.
Abstract
Since 1993, when the first small non-coding RNA was identified, our knowledge about microRNAs has grown exponentially. In this review, we focus on the main progress in this field and discuss the most important findings under a historical perspective. In addition, we examine microRNAs as markers of disease diagnosis and prognosis, and as new therapeutic targets.
Copyright © 2011 Elsevier B.V. All rights reserved.
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