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. 1990 Apr;33(4):167-71.
doi: 10.1111/myc.1990.33.4.167.

Treatment of onychomycosis with a bifonazole-urea combination

F S Hardjoko  1 , S Widyanto, I Singgih, J Susilo
Affiliations

Treatment of onychomycosis with a bifonazole-urea combination

F S Hardjoko et al. Mycoses. 1990 Apr.

Abstract

A clinical trial has been conducted to assess the efficacy of 1% bifonazole and 40% urea ointment for 2 weeks followed by 1% bifonazole cream for one month in the topical treatment of onychomycosis. Thinning and total avulsion of the nails occurred in 97% of 30 patients with candidal onychomycosis and regrowth of a normal appearing nail was found in 92% of 26 patients. Failure rate was 4% and recurrence rate was 12% in 26 patients. Results of the treatment was followed up for 12 weeks. Side effects were negligible.

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