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. 2011 Mar 23;6(3):e17925.
doi: 10.1371/journal.pone.0017925.

Seasonality of MRSA infections

Leonard A Mermel  1 , Jason T Machan, Stephen Parenteau
Affiliations

Seasonality of MRSA infections

Leonard A Mermel et al. PLoS One. .

Abstract

Using MRSA isolates submitted to our hospital microbiology laboratory January 2001-March 2010 and the number of our emergency department (ED) visits, quarterly community-associated (CA) and hospital-associated (HA) MRSA infections were modeled using Poisson regressions. For pediatric patients, approximately 1.85x (95% CI 1.45x-2.36x, adj. p<0.0001) as many CA-MRSA infections per ED visit occurred in the second two quarters as occurred in the first two quarters. For adult patients, 1.14x (95% CI 1.01x-1.29x, adj.p = 0.03) as many infections per ED visit occurred in the second two quarters as in the first two quarters. Approximately 2.94x (95% CI 1.39x-6.21x, adj.p = 0.015) as many HA-MRSA infections per hospital admission occurred in the second two quarters as occurred in the first two quarters for pediatric patients. No seasonal variation was observed among adult HA-MRSA infections per hospital admission. We demonstrated seasonality of MRSA infections and provide a summary table of similar observations in other studies.

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Conflict of interest statement

Competing Interests: Dr. Mermel has served as a consultant for 3M Healthcare and Sage. No other authors have any competing interest to disclose. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Figures

Figure 1
Figure 1. Community-associated MRSA infections along with the model predictions and 95% confidence intervals.
Figure 2
Figure 2. Hospital-associated MRSA infections along with the model predictions and 95% confidence intervals.
See this image and copyright information in PMC

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