doi: 10.1039/c1cc10721f.
Epub 2011 Apr 6.
Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug
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- PMID: 21468443
- DOI: 10.1039/c1cc10721f
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Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug
Chem Commun (Camb).
.
Abstract
Self-assembly supramolecular nanoparticles (SNPs) are synthesized using polyethylenimine (PEI) crosslinked by cyclodextrins (CyDs), adamantyl doxorubicin and plasmid DNA. SNPs successfully conduct the cooperative co-delivery of chemotherapeutic anticancer drug and plasmid DNA in vitro and in vivo.
© The Royal Society of Chemistry 2011
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