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Case Reports
. 1990 Nov;94(5):655-60.
doi: 10.1093/ajcp/94.5.655.

Low-grade primary B-cell lymphoma of the lung. An immunohistochemical, molecular, and cytogenetic study of a single case

A C Wotherspoon  1 , G N Soosay, T C Diss, P G Isaacson
Affiliations
Case Reports

Low-grade primary B-cell lymphoma of the lung. An immunohistochemical, molecular, and cytogenetic study of a single case

A C Wotherspoon et al. Am J Clin Pathol. 1990 Nov.

Abstract

A case of primary low-grade pulmonary lymphoma is described. The histologic features conformed to those laid down by Saltzstein for a diagnosis of "pseudolymphoma." However, the immunocytochemical and molecular investigations confirmed the tumor to be a low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). Cytogenetic studies revealed an abnormal karyotype with a translocation t(1;14). This is the first reported case of an abnormal karyotype in a case of a lymphoma of MALT.

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