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. 1978 Nov 1;21(2):67-9.
doi: 10.1007/BF00240277.

Specific effect of zinc ions on DNA polymerase activity of avian myeloblastosis virus

P R Palan, M L Eidinoff

Specific effect of zinc ions on DNA polymerase activity of avian myeloblastosis virus

P R Palan et al. Mol Cell Biochem. .

Abstract

The effect of selected cations on DNA synthesis by DNA-polymerase of avian myeloblastosis virus (AMV) was studied. Zinc ions at low concentration (0.2mM) in the assay system enhanced the activity about 2 x fold and at higher concentration (2.0 mM) inhibited the activity completely. In contrast, addition of lithium and potassium salts produced inhibitory effects in this ionic concentration range. Replacement of K+ ion had an inhibitory effect on the activity.

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