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Review
. 2011;11(15):1925-43.
doi: 10.2174/156802611796391302.

Thematic Analysis™: a chemogenomic approach to GPCR drug discovery

Roger Crossley  1 , Jacqueline Anne Macritchie, Martin John Slater
Affiliations
Review

Thematic Analysis™: a chemogenomic approach to GPCR drug discovery

Roger Crossley et al. Curr Top Med Chem. 2011.

Abstract

Thematic Analysis™ is a chemogenomic tool which has been developed and used to aid the process of GPCR drug discovery. This review covers the scientific rationale behind the development of this tool and provides examples of the successful application of the chemogenomic method in both hit finding and hit to lead stages of the drug discovery process.

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