Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Apr 26;50(18):4173-5.
doi: 10.1002/anie.201008296. Epub 2011 Apr 6.

Iridium-catalyzed anti-diastereo- and enantioselective carbonyl (α-trifluoromethyl)allylation from the alcohol or aldehyde oxidation level

Affiliations

Iridium-catalyzed anti-diastereo- and enantioselective carbonyl (α-trifluoromethyl)allylation from the alcohol or aldehyde oxidation level

Xin Gao et al. Angew Chem Int Ed Engl. .
No abstract available

PubMed Disclaimer

Figures

Scheme 1
Scheme 1
Elaboration of carbonyl (α-trifluoromethyl)allylation products (as described for Table 1). TBS=tert-butylsilyl, PMB=p-methoxybenzyl, DIPEA=diisopropylethylamine.

Similar articles

Cited by

References

    1. Thayer AM. Chem Eng News. 2006;84:15–24.
    2. Mueller K, Faeh C, Diederich F. Science. 2007;317:1881–1886. - PubMed
    3. Thayer AM. Chem Eng News. 2007;85:11–19.
    1. Carey JS, Laffan D, Thomson C, Williams MT. Org Biomol Chem. 2006;4:2337–2347. - PubMed
    2. Farina V, Reeves JT, Senanayake CH, Song JJ. Chem Rev. 2006;106:2734–2793. - PubMed
    1. For reviews on enantioselective fluorination, see: Ma JA, Cahard D. Chem Rev. 2004;104:6119–6146.Brunet VA, O’Hagan D. Angew Chem. 2008;120:1198–1201.Angew Chem Int Ed. 2008;47:1179–1182.Bobbio C, Gouverneur V. Org Biomol Chem. 2006;4:2065–2075.Audouard C, Ma JA, Cahard D. Adv Org Synth. 2006;2:431–461.Ma JA, Cahard D. Chem Rev. 2008;108:PR1–PR43.Cao LL, Gao BL, Ma ST, Liu ZP. Curr Org Chem. 2010;14:889–916.Ku Kang Y, Kim DY. Curr Org Chem. 2010;14:917–927.Cahard D, Xu X, Couve-Bonnaire S, Pannecoucke X. Chem Soc Rev. 2010;39:558–568.

    1. For reviews on enantioselective trifluoromethylation, see: Ma JA, Cahard D. J Fluorine Chem. 2007;128:975–996.Billard T, Langlois BR. Eur J Org Chem. 2007:891–897.Shibata N, Mizuta S, Kawai H. Tetrahedron: Asymmetry. 2008;19:2633–2644.Nie J, Guo HC, Cahard D, Ma JA. Chem Rev. 2011;111:455–529. and reference [3a].

    1. For aldehyde (trifluoromethyl)allylation and related processes, see: Yamazaki T, Ishikawa N. Chem Lett. 1984:521–524.Hanzawa Y, Ishizawa S, Kobayashi Y, Taguchi T. Chem Pharm Bull. 1990;38:1104–1106.Loh TP, Li XR. Angew Chem. 1997;109:1029–1031.Angew Chem Int Ed Engl. 1997;36:980–982.Loh TP, Li XR. Tetrahedron Lett. 1997;38:869–872.Loh TP, Li XR. Eur J Org Chem. 1999:1893–1899.Sakamoto T, Takahashi K, Yamazaki T, Kitazume T. J Org Chem. 1999;64:9467–9474.Chen Q, Qiu XL, Qing FL. J Org Chem. 2006;71:3762–3767.

Publication types

LinkOut - more resources