Food for thought: neural stem cells on a diet
- PMID: 21474096
- DOI: 10.1016/j.stem.2011.03.004
Food for thought: neural stem cells on a diet
Abstract
Growing evidence shows that stem cells are modulated by systemic factors that are integrated with local signals in response to physiological status. Two recent Cell (Chell and Brand, 2010) and Nature (Sousa-Nunes et al., 2011) papers reveal that Drosophila neural stem cell proliferation is controlled by a diet-dependent insulin/TOR signaling relay between tissues.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Nutrition-responsive glia control exit of neural stem cells from quiescence.Cell. 2010 Dec 23;143(7):1161-73. doi: 10.1016/j.cell.2010.12.007. Cell. 2010. PMID: 21183078 Free PMC article.
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Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila.Nature. 2011 Mar 24;471(7339):508-12. doi: 10.1038/nature09867. Epub 2011 Feb 23. Nature. 2011. PMID: 21346761 Free PMC article.
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