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Case Reports
. 2011;126(2):63-7.
doi: 10.1159/000324799. Epub 2011 Apr 7.

Disseminated Strongyloides stercoralis infection in HTLV-1-associated adult T-cell leukemia/lymphoma

Donn M Stewart  1 , Roshan Ramanathan, Siddhartha Mahanty, Daniel P Fedorko, John E Janik, John C Morris
Affiliations
Case Reports

Disseminated Strongyloides stercoralis infection in HTLV-1-associated adult T-cell leukemia/lymphoma

Donn M Stewart et al. Acta Haematol. 2011.

Abstract

A 55-year-old woman with human T-cell lymphotropic virus type-1 (HTLV-1)-associated adult T-cell leukemia (ATL) and a history of previously treated Strongyloides stercoralis infection received anti-CD52 monoclonal antibody therapy with alemtuzumab on a clinical trial. After an initial response, she developed ocular involvement by ATL. Alemtuzumab was stopped and high-dose corticosteroid therapy was started to palliate her ocular symptoms. Ten days later, the patient developed diarrhea, vomiting, fever, cough, skin rash, and a deteriorating mental status. She was diagnosed with disseminated S. stercoralis. Corticosteroids were discontinued and the patient received anthelmintic therapy with ivermectin and albendazole with complete clinical recovery.

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Figures

Fig. 1
Fig. 1
Skin rash of disseminated Strongyloides.
Fig. 2
Fig. 2
Strongyloides larva in skin.
See this image and copyright information in PMC

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