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Case Reports
. 2011 Apr;31(2):98-100.
doi: 10.3343/kjlm.2011.31.2.98.

Overlapping presence of macroamylasemia and hyperamylasemia in acute pancreatitis

Sun Young Cho, Anbok Lee, Hee Joo Lee, Jin-Tae Suh
Case Reports

Overlapping presence of macroamylasemia and hyperamylasemia in acute pancreatitis

Sun Young Cho et al. Korean J Lab Med. 2011 Apr.
No abstract available

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Findings of abdominal computed tomography performed when the patient showed acute pancreatitis. A cystic lesion (arrows, 1.5 cm) in the pancreatic head region (A) and mild swelling of the pancreas (B) are observed.
Fig. 2
Fig. 2
Trends in the serum amylase and lipase levels from the time of diagnosis of acute pancreatitis (*) to the time of diagnosis of macroamylasemia (**). Serum amylase levels are high for about 4 months, while lipase levels fall near the upper reference limit. Macroamylasemia may occur when lipase level returned to normal, unlike the amylase level, which was sustained at a high level.
Fig. 3
Fig. 3
Serum amylase isoenzyme electrophoresis (A) and capillary electrophoresis (B and C). (A) The P-type amylase level increased to 1,664.13 IU/L (75.30% of the total amylase concentration). The S-type amylase level is within the reference interval (545.87 IU/L; 24.70%). Serum protein capillary electrophoresis (B) and immunotyping (C) show polyclonal gammopathy with a beta-gamma bridge pattern, which is a typical pattern in patients with liver cirrhosis. In immunoglobulin quantification, the estimated IgG and IgA levels were 3,850 mg/dL (reference interval, 700-1,600 mg/dL) and 664 mg/dL (reference interval, 70-400 mg/dL), respectively.
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