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Clinical Trial
. 1990;102(3):379-82.
doi: 10.1007/BF02244107.

Cardiovascular effects of paroxetine

H Kuhs  1 , G A Rudolf
Affiliations
Clinical Trial

Cardiovascular effects of paroxetine

H Kuhs et al. Psychopharmacology (Berl). 1990.

Abstract

In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured.

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