Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011 Feb 16;4(1):82-7.
doi: 10.1159/000324581.

Gemcitabine monotherapy associated with posterior reversible encephalopathy syndrome

Affiliations
Case Reports

Gemcitabine monotherapy associated with posterior reversible encephalopathy syndrome

Luiz Carlos Porcello Marrone et al. Case Rep Oncol. .

Abstract

Posterior reversible encephalopathy syndrome is a clinicoradiologic entity that may present with headaches, altered mental status, seizures and visual loss as well as specific neuroimaging findings. We report a case of a 74-year-old woman receiving adjuvant gemcitabine chemotherapy as monotherapy for a stage IIa pancreatic adenocarcinoma, who developed posterior reversible encephalopathy syndrome.

Keywords: Chemotherapy; Gemcitabine; Posterior reversible encephalopathy syndrome.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Brain MRI showing the subcortical edema in the occipital and temporal lobes.
Fig. 2
Fig. 2
Brain MRI showing a reduction of the subcortical edema.

Similar articles

Cited by

References

    1. Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin MS, Lamy C, Mas JL, Caplan LR. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334:494–500. - PubMed
    1. Sheth RD, Riggs JE, Bodenstenier JB, Gutierrez AR, Ketonen LM, Ortiz OA. Parietal occipital edema in hypertensive encephalopathy: a pathogenic mechanism. Eur Neurol. 1996;36:25–28. - PubMed
    1. Hauser RA, Lacey DM, Knight MR. Hypertensive encephalopathy: magnetic resonance imaging demonstration of reversible cortical and white matter lesions. Arch Neurol. 1988;45:1078–1083. - PubMed
    1. Weingarten K, Barbut D, Filippi C, Zimmerman RD. Acute hypertensive encephalopathy: findings on spin-echo and gradient-echo MR imaging. AJR Am J Roentgenol. 1994;162:665–670. - PubMed
    1. Schwartz RB, Jones KM, Kalina P, Bajakian RL, Mantello MT, Garada B, Holman BL. Hypertensive encephalopathy: findings on CT, MR imaging, and SPECT imaging in 14 cases. AJR Am J Roentgenol. 1992;159:379–383. - PubMed

Publication types