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. 1978 Oct;5(10):3635-42.
doi: 10.1093/nar/5.10.3635.

Definition of the boundaries of the origin of DNA replication in simian virus 40

Free PMC article

Definition of the boundaries of the origin of DNA replication in simian virus 40

K N Subramanian et al. Nucleic Acids Res. 1978 Oct.
Free PMC article

Abstract

We have determined by use of DNA sequencing techniques the exact location of the deletion in d1 892, a viable deletion mutant of Simian virus 40 (SV40) reported to map very near the unique replication origin or SV40. With the help of this localization we have narrowed down the boundaries of the replication origin to 85 nucleotides within the sequence of SV40.

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