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Review
. 2010 Jan;25(1):75-81.
doi: 10.1007/s00467-008-0982-z.

Long-term peritoneal dialysis and encapsulating peritoneal sclerosis in children

Masataka Honda  1 , Bradley A Warady
Affiliations
Review

Long-term peritoneal dialysis and encapsulating peritoneal sclerosis in children

Masataka Honda et al. Pediatr Nephrol. 2010 Jan.

Abstract

Encapsulating peritoneal sclerosis (EPS) is the most serious complication of long-term peritoneal dialysis (PD), with a mortality rate that exceeds 30%. There have been many reports of the incidence of EPS being strongly correlated to the duration of PD. Patients on PD for longer than 5 years, and especially those receiving this treatment for more than 8 years, should undergo careful and repeated surveillance for risk factors associated with the development of EPS. The development of ultrafiltration failure, a high dialysate/plasma creatinine ratio, as determined by the peritoneal equilibration test, peritoneal calcification, a persistently elevated C-reactive protein level, and severe peritonitis in patients on PD for longer than 8 years are signals that should prompt the clinician to consider terminating PD as a possible means of preventing the development of EPS. The impact of the newer, biocompatible PD solutions on the incidence of EPS has not yet been determined.

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Figures

Fig. 1
Fig. 1
Patient survival rate in children initiating peritoneal dialysis before (broken line) and during/after 1992 (solid line). Cited from Honda [12]
Fig. 2
Fig. 2
Technique survival rate in children initiating peritoneal dialysis before (solid line) and during/after 1992 (broken line). Cited from Honda [12]
See this image and copyright information in PMC

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