Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 May;24(5):506-12.
doi: 10.1016/j.echo.2011.02.012. Epub 2011 Apr 7.

Global left atrial strain correlates with CHADS2 risk score in patients with atrial fibrillation

Samir K Saha  1 , Paula L Anderson, Giuseppe Caracciolo, Anatoli Kiotsekoglou, Susan Wilansky, Satish Govind, Naoyo Mori, Partho P Sengupta
Affiliations
Comment

Global left atrial strain correlates with CHADS2 risk score in patients with atrial fibrillation

Samir K Saha et al. J Am Soc Echocardiogr. 2011 May.

Abstract

Background: The aim of this cross-sectional study was to explore the association between echocardiographic parameters and CHADS2 score in patients with nonvalvular atrial fibrillation (AF).

Methods: Seventy-seven subjects (36 patients with AF, 41 control subjects) underwent standard two-dimensional, Doppler, and speckle-tracking echocardiography to compute regional and global left atrial (LA) strain.

Results: Global longitudinal LA strain was reduced in patients with AF compared with controls (P < .001) and was a predictor of high risk for thromboembolism (CHADS2 score ≥ 2; odds ratio, 0.86; P = .02). LA strain indexes showed good interobserver and intraobserver variability. In sequential Cox models, the prediction of hospitalization and/or death was improved by addition of global LA strain and indexed LA volume to CHADS2 score (P = .003).

Conclusions: LA strain is a reproducible marker of dynamic LA function and a predictor of stroke risk and cardiovascular outcomes in patients with AF.

PubMed Disclaimer

Comment on

Publication types