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Case Reports
. 2011 Mar 2:2:132-5.
doi: 10.7150/jca.2.132.

Adult wilms tumor with intracaval and intracardiac extension: report of a case and review of literature

Aitao Guo  1 , Lixin Wei, Xin Song, Aijun Liu
Affiliations
Case Reports

Adult wilms tumor with intracaval and intracardiac extension: report of a case and review of literature

Aitao Guo et al. J Cancer. .

Abstract

Wilms tumor (WT) occurs infrequently in adults. Even rarer is adult WT with extension by direct intravascular spread into the right side of the heart. The present report describes a partially differentiated WT with intracaval and intracardiac extension in a 54-year-old man. The morphologic and immunohistochemical findings confirmed the diagnosis.

Keywords: Wilms tumor; adult; intracardiac extension; intracaval extension.

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Conflict of interest statement

Conflict of Interest: The authors have declared that no conflict of interest exists.

Figures

Figure 1
Figure 1
Multi-plana Reconstruction of CT scan before operation showing a mass in the right renal area and propagation through the inferior vena cava into the right atrium 1A (left). Digital subtraction angiography performed before surgery showing huge tumoral thrombus in the inferior vena cava extension upward from over the right renal vein level 1B (right).
Figure 2
Figure 2
Histological examination of the adult WT. 2A (left) representative of the cystic area. The lining cells of the cysts, ranged from flattened to columnar, were occasionally of “hobnail” type, and the cysts had distinct walls composed of spindle or oval cells. 2B (right) showing a mixture of blastemal and epithelial components with myxoid background in the solid area. [×100]
Figure 3
Figure 3
immunohistochemistry staining of the adult WT. 3A (left) The lining cells of the cysts showed positive staining for cytokeratin and 3B (right) the spindle or oval cells of the cysts walls expressed muscle actin [×200] .
See this image and copyright information in PMC

References

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