Multiple effects of angiopoietin-2 blockade on tumors
- PMID: 21481783
- DOI: 10.1016/j.ccr.2011.03.016
Multiple effects of angiopoietin-2 blockade on tumors
Abstract
In this issue of Cancer Cell, Mazzieri, Pucci, and colleagues describe the marked effects of inhibiting the proangiogenic cytokine, Angiopoietin-2, on tumor angiogenesis and progression in spontaneous tumor models, as well as the proangiogenic functions of TIE2-expressing macrophages.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
-
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.Cancer Cell. 2011 Apr 12;19(4):512-26. doi: 10.1016/j.ccr.2011.02.005. Cancer Cell. 2011. PMID: 21481792
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous