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Comment
. 2011 Apr 12;19(4):431-3.
doi: 10.1016/j.ccr.2011.03.016.

Multiple effects of angiopoietin-2 blockade on tumors

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Multiple effects of angiopoietin-2 blockade on tumors

Claire E Lewis et al. Cancer Cell. .
Free article

Abstract

In this issue of Cancer Cell, Mazzieri, Pucci, and colleagues describe the marked effects of inhibiting the proangiogenic cytokine, Angiopoietin-2, on tumor angiogenesis and progression in spontaneous tumor models, as well as the proangiogenic functions of TIE2-expressing macrophages.

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