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Case Reports
. 2011 Apr;129(4):518-20.
doi: 10.1001/archophthalmol.2011.56.

Rosai-Dorfman disease simulating nodular scleritis and panuveitis

John F Payne, Sunil K Srivastava, Jill R Wells, Hans E Grossniklaus
Case Reports

Rosai-Dorfman disease simulating nodular scleritis and panuveitis

John F Payne et al. Arch Ophthalmol. 2011 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Slitlamp and fundus photographs. A, Slitlamp photograph demonstrates the large perilimbal subconjunctival nodule and fine keratic precipitates. B, Fundus photograph shows hazy media and yellowish subretinal exudates in the inferonasal quadrant. C, Slitlamp photograph 1 month following resection with scleral patch grafting. D, Significant tumor growth had occurred 1 year following resection.
Figure 2
Figure 2
Histopathologic examination. A, Histopathologic examination under low-power magnification demonstrates an infiltration of histiocytes and lymphocytes (hematoxylin-eosin, original magnification ×25). B, Proliferating histiocytes are present with abundant clear cytoplasm (hematoxylin-eosin, original magnification ×100). C, Immunohistochemical staining for S-100 protein was positive. Note the cluster of histiocytes demonstrating emperipolesis (arrow), which is diagnostic for Rosai-Dorfman disease (peroxidase-antiperoxidase, original magnification ×100).
See this image and copyright information in PMC

References

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