Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar;7(3):e1002021.
doi: 10.1371/journal.pcbi.1002021. Epub 2011 Mar 31.

The roots of bioinformatics in theoretical biology

Affiliations

The roots of bioinformatics in theoretical biology

Paulien Hogeweg. PLoS Comput Biol. 2011 Mar.

Abstract

From the late 1980s onward, the term "bioinformatics" mostly has been used to refer to computational methods for comparative analysis of genome data. However, the term was originally more widely defined as the study of informatic processes in biotic systems. In this essay, I will trace this early history (from a personal point of view) and I will argue that the original meaning of the term is re-emerging.

PubMed Disclaimer

Conflict of interest statement

The author has declared that no competing interests exist.

References

    1. Hogeweg P, Hesper B. Interactive instruction on population interactions. Comput Biol Med. 1978;8:319–327. - PubMed
    1. Hogeweg P. Simulating the growth of cellular forms. Simulation. 1978;31:90–96.
    1. Hesper B, Hogeweg P. Bioinformatica: een werkconcept. Kameleon. 1970;1(6):28–29. (In Dutch.) Leiden: Leidse Biologen Club.
    1. Nurse P. Life, logic and information. Nature. 2008;454:424–426. - PubMed
    1. Szekely M. From deoxyribonucleic acid to protein: transfer of genetic information. Wiley 1980

Publication types