Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jun;55(6):3012-4.
doi: 10.1128/AAC.00188-11. Epub 2011 Apr 12.

Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication

Affiliations

Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication

Toshihiro Nishizawa et al. Antimicrob Agents Chemother. 2011 Jun.

Erratum in

  • Antimicrob Agents Chemother. 2013 Feb;57(2):1106

Abstract

A high rate of resistance (49.5 to 72.7%) to amoxicillin (AMX) was observed in Helicobacter pylori after two or three unsuccessful eradication attempts. Unsuccessful eradication regimens significantly increase resistance to not only clarithromycin (CLR) and metronidazole (MNZ) but also AMX.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Clinical and Laboratory Standards Institute 2010. Performance standards for antimicrobial susceptibility testing: twentieth informational supplement, M100-S20. CLSI, Wayne, PA
    1. Hirata K., et al. 2010. Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori. J. Gastroenterol. Hepatol. 25(Suppl. 1):S75–S79 - PubMed
    1. Japan Society for Chemotherapy 2000. Antimicrobial Susceptibility Subcommittee on Helicobacter pylori MIC breakpoints for clarithromycin and amoxicillin. Jpn. Soc. Chemother. 48:561–567
    1. Masaoka T., Suzuki H., Kurabayashi K., Kamiya A. G., Ishii H. 2004. Second-line treatment of Helicobacter pylori infection after dilution agar methods and PCR-RFLP analysis. Aliment. Pharmacol. Ther. 20(Suppl. 1):68–73 - PubMed
    1. Masaoka T., et al. 2006. Could frameshift mutations in the frxA and rdxA genes of Helicobacter pylori be a marker for metronidazole resistance? Aliment. Pharmacol. Ther. 24(Suppl. 4):81–87 - PubMed