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Case Reports
. 2011 Mar 14:5:29-33.
doi: 10.4137/CMC.S6130.

Complete recovery of ischemic cardiomyopathy from thrombotic thrombocytopenic purpura

Sainath Gaddam  1 , Lata Pablani, Vinod Chainani, Ravi Raj Kavuda, Tarun Nagrani, Georges Abou Rjaili, Meekoo Dhar, James C Lafferty
Affiliations
Case Reports

Complete recovery of ischemic cardiomyopathy from thrombotic thrombocytopenic purpura

Sainath Gaddam et al. Clin Med Insights Cardiol. .

Abstract

A 50 year old male HIV patient on antiretroviral therapy was admitted for chest pain. Upon admission, the patient was found to have elevated cardiac enzymes, acute thrombocytopenia, hemolytic anemia, acute pancreatitis and acute renal failure. The patient was diagnosed with thrombotic thrombocytopenic purpura/haemolytic uremic syndrome and emergency plasma exchange therapy was initiated along with aspirin, beta-blockers, steroids, and antiretroviral therapy. Patient responded well and demonstrated complete resolution of ischemic cardiomyopathy with left ventricular ejection fraction improving from 35% to 55% by the time of discharge. Essentially, prompt diagnosis and treatment can reverse cardiac damage induced by thrombotic thrombocytopenic purpura.

Keywords: HIV; cardiomyopathy; thrombotic thrombocytopenic purpura.

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Figures

Figure 1.
Figure 1.
Electrocardiogram showing a sinus rhythm with normal P-waves and PR interval, a normal axis, normal width of QRS complex, with no ST or T wave changes.
See this image and copyright information in PMC

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