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. 2011 May 24;76(21):1838-40.
doi: 10.1212/WNL.0b013e31821ccc72. Epub 2011 Apr 13.

Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis

D A De Silva  1 , J J F Manzano, H M Chang, M C Wong
Affiliations

Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis

D A De Silva et al. Neurology. .

Abstract

Objectives: We reviewed the literature on IV stroke thrombolysis for patients with recent myocardial infarction (MI).

Methods: We searched PubMed and Ovid databases, relevant trials, and guidelines.

Results: Only 5 thrombolyzed stroke patients with recent MI were reported to have cardiac tamponade. Pathological studies show MI healing is completed by 7 weeks.

Conclusion: The time window from MI as a contraindication for IV stroke thrombolysis may be narrowed from 3 months in current guidelines to 7 weeks.

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