Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011:2011:928381.
doi: 10.1155/2011/928381. Epub 2011 Mar 3.

The role of proteoglycans in contributing to placental thrombosis and fetal growth restriction

Joanne M Said  1
Affiliations
Review

The role of proteoglycans in contributing to placental thrombosis and fetal growth restriction

Joanne M Said. J Pregnancy. 2011.

Abstract

Fetal growth restriction is an important pregnancy complication that has major consequences for the fetus and neonate as well as an increased risk of long-term morbidity extending into adulthood. The precise aetiology of most cases of fetal growth restriction is unknown although placental thrombosis is a common feature in many of these cases. This paper will outline the potential role of proteoglycans in contributing to placental thrombosis and fetal growth restriction.

PubMed Disclaimer

References

    1. Barker DJP, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. The Lancet. 1993;341(8850):938–941. - PubMed
    1. Maulik D. Fetal growth restriction: the etiology. Clinical Obstetrics and Gynecology. 2006;49(2):228–235. - PubMed
    1. Maulik D, Frances Evans J, Ragolia L. Fetal growth restriction: pathogenic mechanisms. Clinical Obstetrics and Gynecology. 2006;49(2):219–227. - PubMed
    1. Sugimura M, Ohashi R, Kobayashi T, Kanayama N. Intraplacental coagulation in intrauterine growth restriction: cause or result? Seminars in Thrombosis and Hemostasis. 2001;27(2):107–114. - PubMed
    1. Gerbasi FR, Bottoms S, Farag A, Mammen E. Increased intravascular coagulation associated with pregnancy. Obstetrics and Gynecology. 1990;75(3 I):385–389. - PubMed