The role of proteoglycans in contributing to placental thrombosis and fetal growth restriction
- PMID: 21490795
- PMCID: PMC3065915
- DOI: 10.1155/2011/928381
The role of proteoglycans in contributing to placental thrombosis and fetal growth restriction
Abstract
Fetal growth restriction is an important pregnancy complication that has major consequences for the fetus and neonate as well as an increased risk of long-term morbidity extending into adulthood. The precise aetiology of most cases of fetal growth restriction is unknown although placental thrombosis is a common feature in many of these cases. This paper will outline the potential role of proteoglycans in contributing to placental thrombosis and fetal growth restriction.
Similar articles
-
Decorin expression is decreased in human idiopathic fetal growth restriction.Reprod Fertil Dev. 2010;22(6):949-55. doi: 10.1071/RD09240. Reprod Fertil Dev. 2010. PMID: 20591329
-
Placental syndecan expression is altered in human idiopathic fetal growth restriction.Am J Pathol. 2012 Feb;180(2):693-702. doi: 10.1016/j.ajpath.2011.10.023. Epub 2011 Dec 2. Am J Pathol. 2012. PMID: 22138583
-
Proteoglycans: Systems-Level Insight into Their Expression in Healthy and Diseased Placentas.Int J Mol Sci. 2022 May 21;23(10):5798. doi: 10.3390/ijms23105798. Int J Mol Sci. 2022. PMID: 35628608 Free PMC article. Review.
-
Altered decorin leads to disrupted endothelial cell function: a possible mechanism in the pathogenesis of fetal growth restriction?Placenta. 2014 Aug;35(8):596-605. doi: 10.1016/j.placenta.2014.05.009. Epub 2014 Jun 5. Placenta. 2014. PMID: 24947404
-
The Placental Basis of Fetal Growth Restriction.Obstet Gynecol Clin North Am. 2020 Mar;47(1):81-98. doi: 10.1016/j.ogc.2019.10.008. Epub 2019 Dec 18. Obstet Gynecol Clin North Am. 2020. PMID: 32008673 Review.
Cited by
-
Evaluating the Effect of Utrogestan on Idiopathic Intrauterine Growth Retardation.Adv Biomed Res. 2020 Sep 30;9:45. doi: 10.4103/abr.abr_27_20. eCollection 2020. Adv Biomed Res. 2020. PMID: 33457328 Free PMC article.
References
-
- Barker DJP, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS. Fetal nutrition and cardiovascular disease in adult life. The Lancet. 1993;341(8850):938–941. - PubMed
-
- Maulik D. Fetal growth restriction: the etiology. Clinical Obstetrics and Gynecology. 2006;49(2):228–235. - PubMed
-
- Maulik D, Frances Evans J, Ragolia L. Fetal growth restriction: pathogenic mechanisms. Clinical Obstetrics and Gynecology. 2006;49(2):219–227. - PubMed
-
- Sugimura M, Ohashi R, Kobayashi T, Kanayama N. Intraplacental coagulation in intrauterine growth restriction: cause or result? Seminars in Thrombosis and Hemostasis. 2001;27(2):107–114. - PubMed
-
- Gerbasi FR, Bottoms S, Farag A, Mammen E. Increased intravascular coagulation associated with pregnancy. Obstetrics and Gynecology. 1990;75(3 I):385–389. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical