Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2008 Nov 5;2(3):363-8.
doi: 10.1159/000158543.

Treatment of isolated gastric Crohn's disease with inhaled corticosteroids

Samar H Ibrahim  1 , Thomas C Smyrk, William A Faubion
Affiliations
Case Reports

Treatment of isolated gastric Crohn's disease with inhaled corticosteroids

Samar H Ibrahim et al. Case Rep Gastroenterol. .

Abstract

Isolated gastric Crohn's disease is unusual and a rare cause of pyloric outlet obstruction. If medical therapy is ineffective, patients may require surgery to relieve gastric outlet obstruction. Herein we describe a patient with isolated gastric Crohn's disease with pyloric outlet obstruction who was steroid-dependent and had a relapse despite receiving biologic and immunomodulatory therapy, but ultimately responded to topical treatment with inhaled corticosteroids.

Keywords: Gastric Crohn's disease; Gastric outlet obstruction; Inhaled corticosteroids.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
CT enterography showing dilated stomach.
Fig. 2
Fig. 2
Histological section of a gastric biopsy showing moderate active gastritis before beginning swallowed fluticasone therapy.
Fig. 3
Fig. 3
Histological section of a gastric biopsy showing only mild inflammation six months after beginning swallowed fluticasone therapy.
See this image and copyright information in PMC

References

    1. Auvin S, Molinie F, Gower-Rousseau C, et al. Incidence, clinical presentation and location at diagnosis of pediatric inflammatory bowel disease: a prospective population-based study in northern France (1988-1999) J Pediatr Gastroenterol Nutr. 2005;41:49–55. - PubMed
    1. Fielding JF, Toye DK, Beton DC, Cooke WT. Crohn's disease of the stomach and duodenum. Gut. 1970;11:1001–1006. - PMC - PubMed
    1. Ross TM, Fazio VW, Farmer RG. Long-term results of surgical treatment for Crohn's disease of the duodenum. Ann Surg. 1983;197:399–406. - PMC - PubMed
    1. Murray JJ, Schoetz DJ, Jr, Nugent FW, Coller JA, Veidenheimer MC. Surgical management of Crohn's disease involving the duodenum. Am J Surg. 1984;147:58–65. - PubMed
    1. Futami K, Arima S. Role of strictureplasty in surgical treatment of Crohn's disease. J Gastroenterol. 2005;40(suppl 16):):35–39. - PubMed

Publication types