Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010:2010:865903.
doi: 10.1155/2010/865903. Epub 2010 Jul 18.

Fishermen as a Suitable Population for HIV Intervention Trials

Zachary A Kwena  1 , Craig R Cohen, Norton M Sang, Musa O Ng'ayo, Jeremiah H Ochieng, Elizabeth A Bukusi
Affiliations

Fishermen as a Suitable Population for HIV Intervention Trials

Zachary A Kwena et al. AIDS Res Treat. 2010.

Abstract

Background. Suitable populations to sustain continued evaluation of HIV and sexually transmitted infection (STI) prevention interventions are required. We sought to determine whether fishermen are a suitable population for HIV intervention trials. Methods. In a cross-sectional descriptive survey, we selected 250 fishermen from proportional to size sampled boats. We collected socioeconomic and behavioral information, and specimens for HIV, herpes simplex virus (HSV-2), syphilis, gonorrhea, chlamydia and human papillomavirus (HPV) tests from consenting participants. Results. One third of the fishermen had concurrent sexual partnerships and two thirds were involved in transactional sex. About 70% were involved in extramarital sex with only one quarter using condoms in their three most recent sexual encounters. HIV prevalence was 26% and HSV-2 and HPV was 57%. Over 98% were willing to participate in a future HIV prevention clinical trial. Conclusion. Fishermen are a high-risk group for HIV/STI infections that may be suitable for HIV prevention trials. A cohort study would be useful to measure the incidence of HIV/STIs to ultimately determine the feasibility of enrolling this population in an HIV/STI prevention clinical trial.

PubMed Disclaimer

References

    1. Fleming TR, Richardson BA. Some design issues in trials of microbicides for the prevention of HIV infection. The Journal of Infectious Diseases. 2004;190(4):666–674. - PubMed
    1. Schechter M. HIV vaccine evaluation center in Rio de Janeiro, Brazil. Vaccine. 2002;20(15):1909–1911. - PubMed
    1. Seage GR, III, Holte SE, Metzger D, et al. Are US populations appropriate for trials of human immunodeficiency virus vaccine? The HIVNET vaccine preparedness study. American Journal of Epidemiology. 2001;153(7):619–627. - PubMed
    1. Schechter M, Do Lago RF, De Melo MF, et al. Identification of a high-risk heterosexual population for HIV prevention trials in Rio de Janeiro, Brazil. Journal of Acquired Immune Deficiency Syndromes. 2000;24(2):175–177. - PubMed
    1. Rida W, Fast P, Hoff R, Fleming T. Intermediate-size trials for the evaluation of HIV vaccine candidates: a workshop summary. Journal of Acquired Immune Deficiency Syndromes. 1997;16(3):195–203. - PubMed

LinkOut - more resources