Comparative study of two laser Doppler blood flowmeters

Abstract

A new infrared laser Doppler blood flow instrument (Moor MBF3D) was evaluated using an in vitro model allowing measurements over a range of flow velocities and concentrations. The responses correlated well (r = 0.96, p less than 0.01) with those obtained simultaneously using a Perimed PF3 laser Doppler instrument. The different processing bandwidths of the instruments were investigated and the wideband mode of operation is recommended for flow measurements where there may be fast moving red blood cells (rbcs). The infrared instrument is capable of dual-channel operation, and the two channels are shown to respond almost identically for similar changes in blood flow through the in vitro model (r = 0.999, p less than 0.01). The main advantage of the dual-channel instrument is that continuous measurements may be made simultaneously at two different skin sites allowing dynamic flow responses to be compared.