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. 2011 Jun;101(6):982-5.
doi: 10.2105/AJPH.2010.300066. Epub 2011 Apr 14.

A US policy perspective on oral preexposure prophylaxis for HIV

Arleen A Leibowitz  1 , Karen Byrnes Parker, Mary Jane Rotheram-Borus
Affiliations

A US policy perspective on oral preexposure prophylaxis for HIV

Arleen A Leibowitz et al. Am J Public Health. 2011 Jun.

Abstract

Orally administered preexposure prophylaxis is an innovative and controversial HIV prevention strategy involving the regular use of antiretroviral medications by uninfected individuals. Antiretroviral medications protect against potential HIV infection by reducing susceptibility to the virus. Recent clinical trial results indicate that preexposure prophylaxis can be safe and efficacious for men who have sexual intercourse with men, yet there remain policy considerations surrounding costs, opportunity costs, and ethical issues that must be addressed before broad implementation in the United States.

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References

    1. Garcia-Lerma JG, Paxton L, Kilmarx PH, Heneine W. Oral pre-exposure prophylaxis for HIV prevention. Trends Pharmacol Sci. 2010;31(2):74–81 - PubMed
    1. AIDS Vaccine Advocacy Coalition Ongoing PrEP trials, PrEP trials map. Available at: http://www.avac.org/ht/d/sp/i/3507/pid/3507d/sp/i/3507/pid/3507. Accessed June 3, 2010
    1. Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–2599 - PMC - PubMed
    1. Kim SC, Becker S, Diffenbach C, et al. Planning for pre-exposure prophylaxis to prevent HIV transmission: challenges and opportunities. J Int AIDS Soc. 2010;13:24. - PMC - PubMed
    1. AIDS Vaccine Advocacy Coalition Summary from the AVAC Think Tank on PrEP financing in the US. Available at: http://www.avac.org/ht/d/sp/a/GetDocumentAction/i/3529. Accessed June 3, 2010

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