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. 2011 Apr 8;6(4):e18647.
doi: 10.1371/journal.pone.0018647.

High frequency of chronic bacterial and non-inflammatory prostatitis in infertile patients with prostatitis syndrome plus irritable bowel syndrome

Enzo Vicari  1 , Sandro La Vignera, Domenico Arcoria, Rosita Condorelli, Lucia O Vicari, Roberto Castiglione, Andrea Mangiameli, Aldo E Calogero
Affiliations

High frequency of chronic bacterial and non-inflammatory prostatitis in infertile patients with prostatitis syndrome plus irritable bowel syndrome

Enzo Vicari et al. PLoS One. .

Abstract

Background: Although prostatitis syndrome (PS) and irritable bowel syndrome (IBS) are common disorders, information on the prevalence of IBS in infertile patients with PS is relatively scanty. Therefore, this study was undertaken to estimate the frequency of PS and IBS and to evaluate the prevalence of the various diagnostic categories of prostatitis.

Methodology/principal findings: This study enrolled 152 patients with PS, diagnosed by the NIH-Chronic Prostatitis Symptom Index (NIH-CPSI) in an andrological setting, and 204 patients with IBS, diagnosed according to the Rome III diagnostic criteria in a gastroenterological setting. The patients with PS were asked to fulfill the Rome III questionnaire for IBS, whereas patients with IBS were asked to complete the NIH-CPSI. The simultaneous presence of PS and IBS was observed in 30.2% and 31.8% of the patients screened by andrologists and gastroenterologists, respectively. Altogether, 111 patients had PS plus IBS (31.2%). They had a total NIH-CPSI and pain subscale scores significantly higher than patients with PS alone. Gastrointestinal symptoms in patients with PS plus IBS were similar to those reported by patients with IBS alone and significantly greater in patients with PS alone. Patients with PS plus IBS had a significantly higher frequency of chronic bacterial prostatitis (category II) and lower of non-inflammatory prostatitis (category IIIB), compared to patients with PS alone. The frequency of inflammatory prostatitis (category IIIA) resulted similar.

Conclusions/significance: Prostatitis syndromes and IBS are frequently associated in patients with PS- or IBS-related symptoms. These patients have an increased prevalence of chronic bacterial and non-inflammatory prostatitis.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Roberts RO, Lieber MM, Rhodes T, Girman CJ, Bostwick DJ, et al. Prevalence of a physician-assigned diagnosis of prostatitis: The Olmstead County study of urinary symptoms and health status among men. Urology. 1998;51:578–584. - PubMed
    1. Collins MM, Meigs JB, Barry MJ, Corkery WE, Giovannucci E, et al. Prevalence and correlates of prostatitis in the health professionals follow-up study cohort. J Urol. 2002;167:1363–1366. - PubMed
    1. Wenninger K, Heiman J, Rothman I, Berguis JP, Berger BE. Sickness impact on chronic nonbacterial prostatitis and its correlates. J Urol. 1996;155:965–968. - PubMed
    1. Krieger JN, Egan KJ, Ross SO, Jacobs R, Berger RE. Chronic pelvic pains represent the most prominent urogenital symptoms of ‘Chronic prostatitis’. Urology. 1996;48:715–721. - PubMed
    1. Litwin MS, McNaughton-Collins M, Fowler FJ, Jr, Nickel JC, Calhoun EA, et al. The NIH Chronic Prostatitis Symptom Index (NIH-CPSI): Development and validation of a new outcomes measure. J Urol. 1999;162:364–368. - PubMed

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