Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas
- PMID: 21496551
- DOI: 10.1016/j.jpedsurg.2011.01.012
Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas
Abstract
Infantile hemangioma (IH) is the most common vascular tumor in early childhood. Ulceration is the most frequent complication, and its management can be challenging. We present 6 cases of ulcerated IH at a single pediatric center, which responded to oral propranolol within 2 to 6 weeks. We recommend that oral propranolol therapy be considered for the management of ulcerated IH as first-line treatment.
Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.
Similar articles
-
Propranolol for treatment of ulcerated infantile hemangiomas.J Am Acad Dermatol. 2011 May;64(5):827-32. doi: 10.1016/j.jaad.2010.12.040. Epub 2011 Feb 25. J Am Acad Dermatol. 2011. PMID: 21353332
-
Propranolol, a very promising treatment for ulceration in infantile hemangiomas: a study of 20 cases with matched historical controls.J Am Acad Dermatol. 2011 May;64(5):833-8. doi: 10.1016/j.jaad.2011.01.025. Epub 2011 Feb 25. J Am Acad Dermatol. 2011. PMID: 21353329
-
[Response to oral propranolol therapy for ulcerated hemangiomas in infancy].Arch Pediatr. 2009 Dec;16(12):1565-8. doi: 10.1016/j.arcped.2009.09.008. Epub 2009 Nov 4. Arch Pediatr. 2009. PMID: 19892536 French.
-
Haemangioma: clinical course, complications and management.Br J Dermatol. 2013 Jul;169(1):20-30. doi: 10.1111/bjd.12436. Br J Dermatol. 2013. PMID: 23701395 Review.
-
Successful treatment of ulcerated infantile hemangioma with brimonidine-timolol cream: 2 cases report and review of the literature.J Dermatolog Treat. 2020 Jun;31(4):433-434. doi: 10.1080/09546634.2019.1603991. Epub 2019 Aug 13. J Dermatolog Treat. 2020. PMID: 30973791 Review.
Cited by
-
Management of infantile hemangiomas : current and potential pharmacotherapeutic approaches.Paediatr Drugs. 2013 Apr;15(2):133-8. doi: 10.1007/s40272-013-0008-6. Paediatr Drugs. 2013. PMID: 23456550 Review.
-
Role of propranolol in ulcerated haemangioma of head and neck: a prospective comparative study.Oral Maxillofac Surg. 2016 Mar;20(1):73-7. doi: 10.1007/s10006-015-0528-z. Epub 2015 Oct 20. Oral Maxillofac Surg. 2016. PMID: 26481918 Clinical Trial.
-
The changing face of complicated infantile hemangioma treatment.Pediatr Radiol. 2016 Oct;46(11):1494-506. doi: 10.1007/s00247-016-3643-6. Epub 2016 Jul 23. Pediatr Radiol. 2016. PMID: 27450406 Review.
-
Initiation and use of propranolol for infantile hemangioma: report of a consensus conference.Pediatrics. 2013 Jan;131(1):128-40. doi: 10.1542/peds.2012-1691. Epub 2012 Dec 24. Pediatrics. 2013. PMID: 23266923 Free PMC article. Review.
-
Propranolol in use for treatment of complex infant hemangiomas: literature review regarding current guidelines for preassessment and standards of care before initiation of therapy.ScientificWorldJournal. 2013 May 20;2013:850193. doi: 10.1155/2013/850193. Print 2013. ScientificWorldJournal. 2013. PMID: 23766715 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical