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Comparative Study
. 2011 Jul;70(3):404-7.
doi: 10.1016/j.diagmicrobio.2011.02.006. Epub 2011 Apr 15.

Evaluation of the Xpert™ MRSA/SA Blood Culture assay for the detection of Staphylococcus aureus including strains with reduced vancomycin susceptibility from blood culture specimens

Peter G Kelley  1 , Elizabeth A Grabsch, Jenny Farrell, Shirley Xie, Janet Montgomery, Barrie Mayall, Benjamin P Howden
Affiliations
Comparative Study

Evaluation of the Xpert™ MRSA/SA Blood Culture assay for the detection of Staphylococcus aureus including strains with reduced vancomycin susceptibility from blood culture specimens

Peter G Kelley et al. Diagn Microbiol Infect Dis. 2011 Jul.

Abstract

The Xpert MRSA/SA Blood Culture (BC) assay (Cepheid, Sunnyvale, CA) was prospectively compared to culture and found to have excellent specificity for both Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in BC specimens with a sensitivity of 75% (3/4) and 100% (17/17), respectively. Among 28 heterogeneous vancomycin-intermediate S. aureus (hVISA)/VISA spiked BCs, the assay correctly identified 84.6% VISA and 80% hVISA isolates as MRSA.

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