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Review
. 2011 Jul;32(7):1196-7.
doi: 10.1016/j.neurobiolaging.2011.02.025. Epub 2011 Apr 16.

The epigenetics of Alzheimer's disease--additional considerations

Joseph Rogers  1 , Diego Mastroeni, Andrew Grover, Elaine Delvaux, Charisse Whiteside, Paul D Coleman
Affiliations
Review

The epigenetics of Alzheimer's disease--additional considerations

Joseph Rogers et al. Neurobiol Aging. 2011 Jul.

Abstract

The critical commentaries following our review of the epigenetics of Alzheimer's disease (AD) amplify a number of key points with respect to the role of 1-carbon metabolism, the phenomenon of allele-specific methylation, the potentially critical explanatory link provided by epigenetic mechanisms for genome-wide association and large-scale gene expression array studies, and new therapeutic approaches afforded by epigenetic manipulation in Alzheimer's disease.

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