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. 2011 May 11;133(18):6865-7.
doi: 10.1021/ja1110688. Epub 2011 Apr 18.

Fusarisetin A, an acinar morphogenesis inhibitor from a soil fungus, Fusarium sp. FN080326

Jae-Hyuk Jang  1 , Yukihiro Asami, Jun-Pil Jang, Sun-Ok Kim, Dong Oh Moon, Kee-Sun Shin, Daisuke Hashizume, Makoto Muroi, Tamio Saito, Hyuncheol Oh, Bo Yeon Kim, Hiroyuki Osada, Jong Seog Ahn
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Fusarisetin A, an acinar morphogenesis inhibitor from a soil fungus, Fusarium sp. FN080326

Jae-Hyuk Jang et al. J Am Chem Soc. .

Erratum in

  • J Am Chem Soc. 2012 Apr 25;134(16):7194

Abstract

An acinar morphogenesis inhibitor named fusarisetin A (1) that possesses both an unprecedented carbon skeleton and a new pentacyclic ring system has been identified from an in-house fractionated fungal library using a three-dimensional matrigel-induced acinar morphogenesis assay system. The structure of 1 was determined in detail by NMR and circular dichroism spectroscopy, X-ray analysis, and chemical reaction experiments.

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