The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics
- PMID: 21502417
- DOI: 10.1101/sqb.2010.75.063
The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics
Abstract
The evolutionarily conserved INO80 family of ATP-dependent chromatin-remodeling enzymes has roles in many nuclear processes, including transcription, DNA repair, and DNA replication. Here, we discuss the in vivo and in vitro properties of these enzymes, focusing on recent studies which suggest that members of this family govern the deposition and removal of the histone variant H2A.Z.
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