Clinical and molecular characteristics of extended-spectrum-beta-lactamase-producing Escherichia coli causing bacteremia in the Rotterdam Area, Netherlands
- PMID: 21502612
- PMCID: PMC3122469
- DOI: 10.1128/AAC.00074-11
Clinical and molecular characteristics of extended-spectrum-beta-lactamase-producing Escherichia coli causing bacteremia in the Rotterdam Area, Netherlands
Abstract
We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and molecular characteristics between the 2 community hospitals.
References
-
- Clermont O., et al. 2009. Rapid detection of the O25b-ST131 clone of Escherichia coli encompassing the CTX-M-15-producing strains. J. Antimicrob. Chemother. 64:274–277 - PubMed
-
- Clinical Laboratory Standards Institute 2009. Performance standards for antimicrobial susceptibility testing; 19th informational supplement M100-S19. CLSI, Wayne, PA.
-
- Clinical Laboratory Standards Institute 2010. Performance standards for antimicrobial susceptibility testing; 20th informational supplement M100-S20-U. CLSI, Wayne, PA.
-
- Friedman N. D., et al. 2002. Health care-associated bloodstream infections in adults: a reason to change the accepted definition of community-acquired infections. Ann. Intern. Med. 137:791–797 - PubMed
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