doi: 10.1021/jm200187y.
Epub 2011 May 2.
The medicinal chemist's toolbox: an analysis of reactions used in the pursuit of drug candidates
Affiliations
- PMID: 21504168
- DOI: 10.1021/jm200187y
Item in Clipboard
The medicinal chemist's toolbox: an analysis of reactions used in the pursuit of drug candidates
J Med Chem.
.
No abstract available
Similar articles
-
Timely synthetic support for medicinal chemists.Drug Discov Today. 2005 Jan 15;10(2):115-20. doi: 10.1016/S1359-6446(04)03298-2. Drug Discov Today. 2005. PMID: 15718160 Review.
-
Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates.Bioinformatics. 2005 May 15;21(10):2145-60. doi: 10.1093/bioinformatics/bti314. Epub 2005 Feb 15. Bioinformatics. 2005. PMID: 15713739 Review.
-
Designing active template molecules by combining computational de novo design and human chemist's expertise.J Med Chem. 2007 Apr 19;50(8):1925-32. doi: 10.1021/jm061356+. Epub 2007 Mar 17. J Med Chem. 2007. PMID: 17367122
-
Development of specific "drug-like property" rules for carboxylate-containing oral drug candidates.ChemMedChem. 2010 Dec 3;5(12):2102-13. doi: 10.1002/cmdc.201000355. ChemMedChem. 2010. PMID: 20979082
-
A medicinal chemistry perspective on structure-based drug design and development.Methods Mol Biol. 2012;841:351-81. doi: 10.1007/978-1-61779-520-6_15. Methods Mol Biol. 2012. PMID: 22222460 Review.
Cited by
-
Rhodium-catalyzed boron arylation of 1,2-azaborines.Angew Chem Int Ed Engl. 2013 Aug 26;52(35):9316-9. doi: 10.1002/anie.201304443. Epub 2013 Jul 5. Angew Chem Int Ed Engl. 2013. PMID: 23832871 Free PMC article.
-
Nucleophilic Aromatic Substitution of Unactivated Fluoroarenes Enabled by Organic Photoredox Catalysis.J Am Chem Soc. 2020 Oct 7;142(40):17187-17194. doi: 10.1021/jacs.0c09296. Epub 2020 Sep 28. J Am Chem Soc. 2020. PMID: 32986412 Free PMC article.
-
Enantioconvergent cross-couplings of racemic alkylmetal reagents with unactivated secondary alkyl electrophiles: catalytic asymmetric Negishi α-alkylations of N-Boc-pyrrolidine.J Am Chem Soc. 2013 Jul 31;135(30):10946-9. doi: 10.1021/ja4054114. Epub 2013 Jul 19. J Am Chem Soc. 2013. PMID: 23869442 Free PMC article.
-
Highly reactive, single-component nickel catalyst precursor for Suzuki-Miyuara cross-coupling of heteroaryl boronic acids with heteroaryl halides.Angew Chem Int Ed Engl. 2012 Dec 14;51(51):12837-41. doi: 10.1002/anie.201207428. Epub 2012 Nov 7. Angew Chem Int Ed Engl. 2012. PMID: 23136047 Free PMC article. No abstract available.
-
Electrochemical Decarboxylative N-Alkylation of Heterocycles.Org Lett. 2020 Oct 2;22(19):7594-7598. doi: 10.1021/acs.orglett.0c02799. Epub 2020 Sep 17. Org Lett. 2020. PMID: 32941044 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
