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. 2011 Jun;34(6):1337-43.
doi: 10.2337/dc10-2251. Epub 2011 Apr 19.

Trends in the risk for coronary heart disease among adults with diagnosed diabetes in the U.S.: findings from the National Health and Nutrition Examination Survey, 1999-2008

Earl S Ford  1
Affiliations

Trends in the risk for coronary heart disease among adults with diagnosed diabetes in the U.S.: findings from the National Health and Nutrition Examination Survey, 1999-2008

Earl S Ford. Diabetes Care. 2011 Jun.

Abstract

Objective: Coronary heart disease (CHD) is a major cause of mortality among people with diabetes. The objective of this study was to examine the trend in an estimated 10-year risk for developing CHD among adults with diagnosed diabetes in the U.S.

Research design and methods: Data from 1,977 adults, aged 30-79 years, with diagnosed diabetes who participated in the National Health and Nutrition Examination Survey from 1999-2000 to 2007-2008 were used. Estimated risk was calculated using risk prediction algorithms from the UK Prospective Diabetes Study (UKPDS), the Atherosclerosis Risk in Communities study, and the Framingham Heart Study.

Results: Significant improvements in mean HbA(1c) concentrations, systolic blood pressure, and the ratio of total cholesterol to HDL cholesterol occurred. No significant linear trend for current smoking status was observed. The estimated UKPDS 10-year risk for CHD was 21.1% in 1999-2000 and 16.4% in 2007-2008 (P(linear trend) < 0.001). The risk decreased significantly among men, women, whites, African Americans, and Mexican Americans.

Conclusions: The estimated 10-year risk for CHD among adults with diabetes has improved significantly from 1999-2000 to 2007-2008. Sustained efforts in improving risk factors should further benefit the cardiovascular health of people with diabetes.

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Figures

Figure 1
Figure 1
Estimated 10-year risk (95% CI) for developing CHD among adults with diagnosed diabetes in the U.S. by race or ethnicity (NHANES). A: UKPDS risk estimates among participants aged 30–79 years. B: ARIC study risk estimates among participants aged 45–65 years. C: FHS risk estimates among participants aged 30–74 years.
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References

    1. Centers for Disease Control and Prevention. Trends in current cigarette smoking among high school students and adults, United States, 1965–2007 [article online], 2010. Available at http://www.cdc.gov/tobacco/data_statistics/tables/trends/cig_smoking/ind... Accessed 18 April 2011
    1. Carroll MD, Lacher DA, Sorlie PD, et al. Trends in serum lipids and lipoproteins of adults, 1960-2002. JAMA 2005;294:1773–1781 - PubMed
    1. Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008. JAMA 2010;303:2043–2050 - PubMed
    1. Hoerger TJ, Zhang P, Segel JE, Gregg EW, Narayan KM, Hicks KA. Improvements in risk factor control among persons with diabetes in the United States: evidence and implications for remaining life expectancy. Diabetes Res Clin Pract 2009;86:225–232 - PubMed
    1. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey [article online], 2010. Available at http://www.cdc.gov/nchs/nhanes.htm Accessed 18 April 2011

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