Emergency evacuation! Hematopoietic niches induce cell exit in infection
- PMID: 21511181
- DOI: 10.1016/j.immuni.2011.04.009
Emergency evacuation! Hematopoietic niches induce cell exit in infection
Abstract
The roles of hematopoietic stem and/or progenitor cell niches during infection remain unclear. In this issue of Immunity, Shi et al. (2011) reveal that these niches upregulate MCP1 chemokine expression, inducing emigration of bone marrow monocytes into the circulation via the endothelium.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands.Immunity. 2011 Apr 22;34(4):590-601. doi: 10.1016/j.immuni.2011.02.016. Epub 2011 Mar 31. Immunity. 2011. PMID: 21458307 Free PMC article.
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