Control of rat skeletal-muscle phosphorylase phosphatase activity by adrenaline
- PMID: 215133
- PMCID: PMC1186236
- DOI: 10.1042/bj1760347
Control of rat skeletal-muscle phosphorylase phosphatase activity by adrenaline
Abstract
Administration of adrenaline to an isolated rat hindlimb preparation rapidly decreased muscle phosphorylase phosphatase (EC 3.1.3.17) activity and increased heat-stable and trypsin-labile phosphatase inhibitor activity. This was associated with increased tissue cyclic AMP concentrations, phosphorylase (EC 2.4.1.1) activation and glycogen synthase (EC 2.4.1.11) inactivation.
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