Taking the gonococcus-human relationship to a whole new level: implications for the coevolution of microbes and humans
- PMID: 21521723
- PMCID: PMC3087451
- DOI: 10.1128/mBio.00067-11
Taking the gonococcus-human relationship to a whole new level: implications for the coevolution of microbes and humans
Abstract
While horizontal gene transfer occurs frequently among bacterial species, evidence for the transfer of DNA from host to microbe is exceptionally rare. However, the recent report by Anderson and Seifert [mBio 2(1):e00005-11, 2011] provides evidence for such an event with the finding that 11% of Neisseria gonorrhoeae strains harbor a 685-bp sequence that is 98 to 100% identical to the human long interspersed nuclear element L1. While the function of this element in gonococci remains unclear, this finding significantly impacts our consideration of the coevolution of hosts and microbes, particularly that of humans and pathogens.
Comment on
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Opportunity and means: horizontal gene transfer from the human host to a bacterial pathogen.mBio. 2011 Feb 15;2(1):e00005-11. doi: 10.1128/mBio.00005-11. Print 2011. mBio. 2011. PMID: 21325040 Free PMC article.
References
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- Brinkmann V, et al. 2004. Neutrophil extracellular traps kill bacteria. Science 303:1532–1535 - PubMed
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