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. 2010 Dec 11;67(Pt 1):o59.
doi: 10.1107/S1600536810050749.

(3R,6R,12R,20S,24S)-3,6,12-Triacetyl-20,24-ep-oxy-dammarane-3,6,12,25-tetra-ol

Huan-Mei Guo, Liang Wang, Nan Wang, Jiang-Feng Zhang, Qing-Guo Meng

(3R,6R,12R,20S,24S)-3,6,12-Triacetyl-20,24-ep-oxy-dammarane-3,6,12,25-tetra-ol

Huan-Mei Guo et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The title compound, C(36)H(58)O(8), was prepared from 20(S)-protopanaxatriol, which was degraded from Panax quinquefolium saponin with sodium in glycerine, extracted and seperated by flash chromatography. Three six-membered rings are in chair conformations, the five-membered ring is in an envelope form and the tetra-hydro-furan ring has a conformation inter-mediate between half-chair and envelope. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, and C-H⋯O contacts also occur. The absolute structure was assigned on the basis of the synthesis.

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Figures

Fig. 1.
Fig. 1.
The molecular structure of the title compound with displacement ellipsoids drawn at the 30% probability level.
See this image and copyright information in PMC

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