1-(2-Benzoyl-1-phenyl-eth-yl)-4-[(2-hy-droxy-1-naphth-yl)methyl-idene-amino]-3-methyl-1H-1,2,4-triazole-5(4H)-thione
- PMID: 21522961
- PMCID: PMC3051504
- DOI: 10.1107/S1600536810052979
1-(2-Benzoyl-1-phenyl-eth-yl)-4-[(2-hy-droxy-1-naphth-yl)methyl-idene-amino]-3-methyl-1H-1,2,4-triazole-5(4H)-thione
Abstract
In the title compound, C(29)H(24)N(4)O(2)S, intra-molecular O-H⋯N hydrogen bonding influences the mol-ecular conform-ation; the naphthol system and triazole ring form a dihedral angle of 3.88 (7)°. In the crystal, π-π inter-actions between the five- and six-membered rings of neighbouring mol-ecules [centroid-centroid distances = 3.541 (3) and 3.711 (3) Å] consolidate the crystal packing.
Figures
References
-
- Allen, F. H., Kennard, O., Watson, D. G., Brammer, L., Orpen, A. G. & Taylor, R. (1987). J. Chem. Soc. Perkin Trans. 2, pp. S1–19.
-
- Ferlin, M. G., Chiarelotto, G., Antonucci, F., Caparrotta, L. & Froldi, G. (2002). Eur. J. Med. Chem. 37, 427–434. - PubMed
-
- Holla, B. S., Veerendra, B., Shivananda, M. K. & Poojary, B. (2003). Eur. J. Med. Chem. 38, 759–767. - PubMed
-
- Joshi, S., Khosla, N. & Tiwari, P. (2004). Bioorg. Med. Chem. 12, 571–576. - PubMed
-
- Negm, N. A., Morsy, S. M. I. & Said, M. M. (2005). Bioorg. Med. Chem. Lett. 13, 5921–5926. - PubMed
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous