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Review
. 2011 May;34 Suppl 2(Suppl 2):S279-84.
doi: 10.2337/dc11-s231.

Long-acting glucagon-like peptide 1 receptor agonists: a review of their efficacy and tolerability

Affiliations
Review

Long-acting glucagon-like peptide 1 receptor agonists: a review of their efficacy and tolerability

Alan J Garber. Diabetes Care. 2011 May.
No abstract available

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Figures

Figure 1
Figure 1
Change in A1C with long-acting GLP-1 receptor agonists across the clinical trials (,,–39,41). *P < 0.01 vs. comparator; **P < 0.001; ***P < 0.0001; ###P < 0.0001 vs. placebo.
Figure 2
Figure 2
Change in body weight with long-acting GLP-1 receptor agonists across the clinical trials (,,–39,41). **P < 0.001; ***P < 0.0001.

References

    1. Kahn SE, Haffner SM, Heise MA, et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006;355:2427–2443 - PubMed
    1. UK Prospective Diabetes Study (UKPDS) Group Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837–853 - PubMed
    1. Nathan DM, Buse JB, Davidson MB, et al. Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 2009;52:17–30 - PubMed
    1. Rodbard HW, Jellinger PS, Davidson JA, et al. Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: an algorithm for glycemic control. Endocr Pract 2009;15:540–559 - PubMed
    1. American Diabetes Association Standards of medical care in diabetes—2009. Diabetes Care 2009;32(Suppl. 1):S13–S61 - PMC - PubMed

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